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Hidden Link Between Artificial Sweeteners and Chronic Pain

October 28, 2025

If you are living with chronic back or neck pain, you've probably experimented with everything—stretches, heating pads, over-the-counter medications. But have you thought about the impact your diet drinks and “sugar-free” snacks may have? Developing research intimates that artificial sweeteners might be harming your pain relief efforts through an unexpected pathway: your gut. Amelia Chiropractic Clinic is here to explore any potential avenues to help you get back to enjoying your life!

THE GUT-PAIN CONNECTION

Your gut isn't just in charge of digestion—it's home to trillions of microorganisms that impact inflammation throughout your entire body, including your spine and neck. Recent groundbreaking research has revealed a direct link between artificial sweeteners, gut health, and chronic pain sensitivity.

A 2025 Mendelian randomization study by Zhao and colleagues demonstrated that artificially sweetened foods can truly cause chronic pain by disrupting the gut microbiota. (1) This isn't just correlation—the research shows a causal relationship between using these sweeteners and higher pain levels.

HOW SWEETNERS TRIGGER PAIN

Artificial sweeteners can alter the balance of beneficial bacteria living in your digestive system. These upset microbes trigger inflammatory responses that go throughout your body. As described in a comprehensive 2019 review by Guo and colleagues in the British Journal of Anaesthesia, the gut microbiota directly regulates pain through multiple molecular mechanisms, including immune system activation and nerve sensitivity. (2)

For back and neck pain sufferers seeking help at Amelia Chiropractic Clinic, this inflammation can raise pain sensitivity in already vulnerable areas. Your spinal nerves become more reactive, making an already uncomfortable situation worse and potentially slowing your recovery.

TAKING ACTION

Before your next chiropractic appointment, consider eliminating artificial sweeteners from your diet. This would involve checking labels on diet sodas, protein bars, yogurts, and sugar-free desserts for ingredients like aspartame, sucralose, and saccharin

Chiropractic physicians recognize that pain management demands a whole-body approach. While spinal adjustments focus on mechanical dysfunction, reducing inflammation through dietary modifications can significantly raise treatment outcomes. By sustaining your gut health, you're creating an internal environment more advantageous to healing and less responsive to pain signals. Small dietary changes might be a valuable extra to your pain relief strategy with Amelia Chiropractic Clinic.

Your path to back pain relief and/or neck pain relief may begin with what you remove from your shopping cart.

CONTACT Amelia Chiropractic Clinic

Listen to this PODCAST with Dr. James Cox, on The Back Doctors Podcast with Dr. Michael Johnson as he illustrates the impact inflammation has on the immune system and the help chiropractic care like The Cox® Technic System of Spinal Pain Management that Fernandina Beach chiropractic patients may experience.

Make your Fernandina Beach chiropractic appointment today.