Fernandina Beach Back Pain Related to Inflammation Reduced with Melatonin

Inflammation. Disc Degeneration. There is a connection. Inflammation acts as the body’s response system to harmful stimuli (injury, pathogens, metabolic stress – a disc herniation pushing on a nerve!) as it attempts to restore itself to normal before the harm was achieved. Amelia Chiropractic Clinic is always amazed at how the body takes care of itself! Amelia Chiropractic Clinic sees its Fernandina Beach chiropractic care as a partner of the body’s system in healing especially when spine pain is an issue. Chiropractic care utilizes many tools like spinal manipulation, exercise, and nutrition to help the body. Melatonin is one nutritional tool that is proving value by interrupting the inflammatory process related disc herniation that brings about pain relief: back, neck, spine-related.

DISC DEGENERATION AND INFLAMMATION AND 'AUTOPHAGY'

Inflammatory markers interleukin-1β (IL-1β), interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) are linked to intervertebral disc degeneration. (1) IL-1 β in fact promotes itself, its own expression, by upregulating NLRP3 inflammasome activation. (2) The body controls itself down to the cellular level via autophagy, the natural process during which the body’s cells clean out damaged (ie, by inflammation) or unneeded parts. In a recent study, melatonin increased autophagy and lessened the degradation of the disc’s extracellular matrix (technically marked by a decline in marker LC3B, autophagasomes and autolysosomes and inhibition of the NF-kB signaling pathway). The end conclusion was that melatonin inhibits intervertebral disc degeneration by promoting autophagy. (3) Wow. Amelia Chiropractic Clinic is inspired by this research to see just how well melatonin can work for Fernandina Beach back pain related to disc degeneration.

MELATONIN AND ITS HEALING WAYS FOR THE DISC

Disc degeneration is such a common condition seen at Amelia Chiropractic Clinic making positive news like this quite rousing. A new study explained how melatonin could modulate the extracellular matrix of the disc remodeling process started by IL-1 β. Additionally, melatonin decreased the inflammatory cell collection and decreased the release of associated inflammatory markers IL-1β, IL-6, and TNF-α. With this new finding that melatonin disrupted the IL-1B feedback loop, researchers postulated that melatonin may provide the restoration process of intervertebral discs after damage was already present. (1) Amelia Chiropractic Clinic continues following the new research on the role inflammation plays in Fernandina Beach disc degeneration and melatonin’s role in reducing it.

INFLAMMATION AND MELATONIN

The importance of melatonin in helping to slow or stop painful conditions due to inflammation is rising. The description of melatonin as a multitasking molecule influencing mood, immunity, and energy among other things is quite appropriate. It’s also anti-oxidant, anti-aging, and anti-inflammatory, specifically by blocking the activation of inflammasomes (4) Melatonin’s formal chemical name is as about as long as its list of tasks: N-acetyl-5-methoxytryptamine. The pineal gland secretes melatonin naturally. Melatonin influences the body’s aging, anti-inflammatory, anti-apoptosis (cell death), and autophagy (cell-cleanout) processes. (1) Melatonin’s specific influence on inflammation and disc degeneration is most attention-getting to Amelia Chiropractic Clinic and our Fernandina Beach back pain patients.

CONTACT Amelia Chiropractic Clinic

Listen to this PODCAST with Dr. Hrefna Sylvia based in Iceland where back pain isn’t much different from any other country on The Back Doctors Podcast with Dr. Michael Johnson as she describes how The Cox® Technic System of Spinal Pain Management manages disc degeneration for relief of chronic low back pain in her patient.

Schedule your Fernandina Beach chiropractic appointment with Amelia Chiropractic Clinic today. We can discuss the role inflammation plays in your back pain experience and how melatonin may help with the related disc degeneration.

 
Amelia Chiropractic Clinic presents new findings that melatonin interrupts the inflammatory process in disc degeneration that causes back pain. 
 
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"This information and website content is not intended to diagnose, guarantee results, or recommend specific treatment or activity. It is designed to educate and inform only. Please consult your physician for a thorough examination leading to a diagnosis and well-planned treatment strategy. See more details on the DISCLAIMER page. Content is reviewed by Dr. James M. Cox I."